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Bharat Bhattarai, Ph.D.

Chemistry | Assistant Professor

Ph.D. in Chemistry and Molecular Cell Biology (2009) – Inha University; Incheon, South Korea.
M.Sc. in Chemistry Specialized in Inorganic Chemistry (1999) – Tribhuvan University, Kathmandu, Nepal.
Dr. Bharat Bhattarai joined Waldorf University in August 2019. Before coming to Waldorf, he was teaching different Chemistry courses at Springfield College, American International College and Springfield Technical Community College at Springfield, Mass.

Dr. Bhattarai’s research interest lie on design, discovery and development of novel anti-diabetes and anti-cancer drugs utilizing the several medicinal chemistry and biochemistry approaches. To achieve these goals, he utilizes broad range of chemical and biological techniques, such as screening of chemical library, synthesis of small organic molecule and SAR studies, bacterial and mammalian cell cultures, several target protein expression and purification, enzyme kinetics assays, gel electrophoresis, western blot, PCR, fluorescence microscopy, flow cytometry, DNA manipulation and in vitro and in vivo enzyme assays. His expertise in such a wide range of research techniques gives our students a great opportunity to learn experimental techniques and gain research experiences to pursue their career in Chemistry or Health Science related areas.

Dr. Bhattarai has published several papers in peer-reviewed international scientific journals. He has also presented his research in a dozen of national and international meetings and conferences.

Bharat lives in Forest City with his wife, Suravi, and two beautiful kids, Shuva and Shreeja. He loves spending his leisure time with family. They enjoy camping, hiking, cycling and, of course, shopping as soon as they get the opportunity.

Professional Experience:
Postdoctoral Fellow (2010-13)–Department of Chemistry, University of Connecticut, Storrs, Conn.
Postdoctoral Fellow (2009-10)–Faculty of Pharmacy, University of Manitoba, Winnipeg, Canada.

Selected Publications:
1. Gaik-Lean Chee, Bharat Bhattarai, Jordan D. Nash, Kim Madec, Brian B. Hasinoff, and A. David Brewer, Chemical reactivity and biological activity of dihydro-1,4- dithiin tetraoxides. Can. J. Chem. 91, 649-655 (2013).
2. Gaik-Lean Chee, Bharat Bhattarai, R. Daniel Gietz, Samaa Alrushaid, John L. Nittis, and Brian B. Hasinoff; Chemical reactivity and microbicidal action of Bethoxazin. Bioorg. Med. Chem. 20, 1494-1501, (2012)
3. Bharat Raj Bhattarai, Bhooshan Kafle, Ji-Sun Hwang, Seung Wook Ham, Keun- Hyeung Lee, Hwangseo Park, Inn-Oc Han, and Hyeongjin Cho; Novel thiazolidinedione derivatives with anti-obesity effects: Dual action as PTP1B inhibitors and PPAR-γ activators. Bioorg. Med. Chem. Lett., 20, 6758-6763, (2010).
4. Bharat Raj Bhattarai, Jeong-Hyeon Ko, Suja Shrestha, Bhooshan Kafle, Heeyeong Cho, Ju-Hee Kang, and Hyeongjin Cho; Inhibition of IKK-β: a new development in the mechanism of the anti-obesity effects of PTP1B inhibitors SA18 and SA32. Bioorg. Med. Chem. Lett., 20, 1075-1077, (2010).
5. Bharat Raj Bhattarai, Bhooshan Kafle, Ji-Sun Hwang, Deegendra Khadka, Sun- Myung Lee, Jae-Seung Kang, Seung Wook Ham, Inn-Oc Han, Hwangseo Park, and Hyeongjin Cho; Thiazolidinedione derivatives as PTP1B inhibitors with antihyperglycemic and antiobesity effects. Bioorg. Med. Chem. Lett., 19, 6161- 6165, (2009).